MHC class II deficiency: a disease of gene regulation
J Villard, K Masternak, B Lisowska-Grospierre… - Medicine, 2001 - journals.lww.com
Primary human immunodeficiencies constitute a heterogenous group of inborn errors of the
immune system due to a variety of genetic abnormalities. The study of patients with primary
immunodeficiency diseases has expanded our understanding of immunity. Recent progress
in immunobiology and genetics has identified with increasing precision the causes of many
primary immunodeficiencies; diagnosis and therapy, as a result, can be more specific and
effective (26, 87).
immune system due to a variety of genetic abnormalities. The study of patients with primary
immunodeficiency diseases has expanded our understanding of immunity. Recent progress
in immunobiology and genetics has identified with increasing precision the causes of many
primary immunodeficiencies; diagnosis and therapy, as a result, can be more specific and
effective (26, 87).
