[74] Hormone-sensitive lipase from adipose tissue of rat
G Fredrikson, P Strålfors, NÖ Nilsson, P Belfrage - Methods in enzymology, 1981 - Elsevier
Hormone-sensitive lipase (HSL) 1 catalyzes the step that, under normal conditions, is rate-
limiting in the breakdown of the stored lipids of adipose tissue: the hydrolysis of the first ester
bond of the triacylglycerol. It also catalyzes the hydrolysis of the diacylglycerol produced and
at least part of the monoacylglycerol. 2.3 The activity of the enzyme, and thus the overall
lipolysis rate in the adipocyte, changes in response to a variety of hormones. 4 This
regulation has, for a number of years, been thought to be associated with a cyclic AMP and …
limiting in the breakdown of the stored lipids of adipose tissue: the hydrolysis of the first ester
bond of the triacylglycerol. It also catalyzes the hydrolysis of the diacylglycerol produced and
at least part of the monoacylglycerol. 2.3 The activity of the enzyme, and thus the overall
lipolysis rate in the adipocyte, changes in response to a variety of hormones. 4 This
regulation has, for a number of years, been thought to be associated with a cyclic AMP and …
