Permselectivity of the glomerular capillary wall: III. Restricted transport of polyanions

RLS Chang, WM Deen, CR Robertson, BM Brenner - Kidney international, 1975 - Elsevier
RLS Chang, WM Deen, CR Robertson, BM Brenner
Kidney international, 1975Elsevier
Methods Animal Studies. Studies were performed on ten male and female Munich-Wistar
rats weighing 216 to 292 g and allowed free access to water and a standard rat pellet diet. 1)
Studies with dextran sulfate molecules of narrow size distribution. Initial studies were
performed to determine whether fractional dextran sulfate (DS) clearances obtained for the
kidney as a whole (estimated from comparison of the urine-to-plasma water concentration
ratios of various sized DS molecules (U/P) Ds, to simultaneously measured ratios for inulin …
Methods
Animal Studies. Studies were performed on ten male and female Munich-Wistar rats weighing 216 to 292 g and allowed free access to water and a standard rat pellet diet.
1) Studies with dextran sulfate molecules of narrow size distribution. Initial studies were performed to determine whether fractional dextran sulfate (DS) clearances obtained for the kidney as a whole (estimated from comparison of the urine-to-plasma water concentration ratios of various sized DS molecules (U/P) Ds, to simultaneously measured ratios for inulin (U/P) JN) can be equated with
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