[HTML][HTML] Mobilization of hematopoietic primitive and committed progenitor cells into blood in mice by anti-vascular adhesion molecule-1 antibody alone or in …
T Kikuta, C Shimazaki, E Ashihara, Y Sudo… - Experimental …, 2000 - Elsevier
OBJECTIVE: One of the mechanisms for mobilization of hematopoietic stem cells and
progenitor cells is alternation of adhesion molecules. We investigated the mobilization of
hematopoietic progenitor cells in blood by administration of anti-vascular cell adhesion
molecule (VCAM)-1 antibody (Ab) in mice. MATERIALS AND METHODS: Twelve-to 14-week-
old C57BL/6J mice were injected intravenously with anti-VCAM-1 Ab and anti-very late
antigen (VLA)-4 Ab at a dose of 5 mg/kg for 2 days. RESULTS: The number of colony …
progenitor cells is alternation of adhesion molecules. We investigated the mobilization of
hematopoietic progenitor cells in blood by administration of anti-vascular cell adhesion
molecule (VCAM)-1 antibody (Ab) in mice. MATERIALS AND METHODS: Twelve-to 14-week-
old C57BL/6J mice were injected intravenously with anti-VCAM-1 Ab and anti-very late
antigen (VLA)-4 Ab at a dose of 5 mg/kg for 2 days. RESULTS: The number of colony …