Hyperprolactinemia in acute myeloid leukemia and indication of ectopic expression of human prolactin in blast cells of a patient of subtype M4
SJ Hatfill, R Kirby, M Hanley, E Rybicki, L Böhm - Leukemia research, 1990 - Elsevier
The sera of 28 patients with acute myeloid leukemia AML—subtypes M1 to M6 were
screened for human prolactin (h-PRL). Serum TSH (thyroid stimulating hormone), LH
(luteinizing hormone), FSH (follicle stimulating hormone), β-estradiol, free T4 (tetra-
iodotyronine) and testosterone were also determined. It was found that in 16 of the 28
patients h-PRL was significantly elevated while all other endocrine values were normal. In a
patient subtype M4 with elevated serum h-PRL we demonstrate by immunoblotting that the …
screened for human prolactin (h-PRL). Serum TSH (thyroid stimulating hormone), LH
(luteinizing hormone), FSH (follicle stimulating hormone), β-estradiol, free T4 (tetra-
iodotyronine) and testosterone were also determined. It was found that in 16 of the 28
patients h-PRL was significantly elevated while all other endocrine values were normal. In a
patient subtype M4 with elevated serum h-PRL we demonstrate by immunoblotting that the …