The complement system in hemolytic-uremic syndrome in childhood.

L Monnens, J Molenaar, PH Lambert… - Clinical …, 1980 - europepmc.org
L Monnens, J Molenaar, PH Lambert, W Proesmans, P Van Munster
Clinical Nephrology, 1980europepmc.org
A dynamic estimation of the complement system was obtained by immunochemical
estimation of C3, C4, C5, C1q, C3b+ C3c, C3d, Ba in children with hemolytic-uremic
syndrome. The presence of increased breakdown products of C3 (C3b+ C3c, C3d) and of
factor B (Ba) suggests an activation of the complement system possibly by the alternative
pathway. No definite explanation for these complement abnormalities can be given.
A dynamic estimation of the complement system was obtained by immunochemical estimation of C3, C4, C5, C1q, C3b+ C3c, C3d, Ba in children with hemolytic-uremic syndrome. The presence of increased breakdown products of C3 (C3b+ C3c, C3d) and of factor B (Ba) suggests an activation of the complement system possibly by the alternative pathway. No definite explanation for these complement abnormalities can be given.
europepmc.org