Anandamide suppresses nitric oxide and TNF-α responses to Theiler's virus or endotoxin in astrocytes
F Molina-Holgado, A Lledó, C Guaza - Neuroreport, 1997 - journals.lww.com
ASTROCYTES are an important cell population in the CNS, involved in cytokine
homeostasis and participating in a variety of important physiological and pathological
processes. In the present study we showed that primary cultures of neonatal mouse cortical
astrocytes stimulated with lipopolysaccharide (Balb/c mice strain, LPS: 1 μg/ml, 18 h) or
Theiler's virus, TMEV (SJL/J mice strain, TMEV: 10 5 PFU/well, 24 h) released an increased
amount of nitrites (NO 2−) and tumour necrosis factor-α (TNF-α) into the culture medium …
homeostasis and participating in a variety of important physiological and pathological
processes. In the present study we showed that primary cultures of neonatal mouse cortical
astrocytes stimulated with lipopolysaccharide (Balb/c mice strain, LPS: 1 μg/ml, 18 h) or
Theiler's virus, TMEV (SJL/J mice strain, TMEV: 10 5 PFU/well, 24 h) released an increased
amount of nitrites (NO 2−) and tumour necrosis factor-α (TNF-α) into the culture medium …
