Deficits in small interneurons in prefrontal and cingulate cortices of schizophrenic and schizoaffective patients
FM Benes, J McSparren, ED Bird… - Archives of general …, 1991 - jamanetwork.com
• A recent report suggested that neurons in the prefrontal, anterior cingulate, and primary
motor cortex of the brains of schizophrenic subjects may be less dense than those in the
brains of nonschizophrenic subjects. We have determined whether pyramidal neurons
and/or interneurons are preferentially reduced in schizophrenic subjects. Twelve control
subjects and 18 schizophrenic subjects were studied in a blind, quantitative analysis of the
density of pyramidal cells, interneurons, and glial cells in each of the six layers of the …
motor cortex of the brains of schizophrenic subjects may be less dense than those in the
brains of nonschizophrenic subjects. We have determined whether pyramidal neurons
and/or interneurons are preferentially reduced in schizophrenic subjects. Twelve control
subjects and 18 schizophrenic subjects were studied in a blind, quantitative analysis of the
density of pyramidal cells, interneurons, and glial cells in each of the six layers of the …
