The intracellular fatty acid content of insulin-sensitive target tissues determines in part their
insulin sensitivity. Uptake of fatty acids into cells is a controlled process determined in part
by a regulated import/export system that is controlled at least by two key groups of proteins,
ie the fatty acid transport protein (FATP) and acyl-CoA synthetase (ACS), which facilitate,
respectively, the transport of fatty acids across the cell membrane and catalyze their
esterification to prevent their efflux. Previously it was shown that the expression of theFATP …