[HTML][HTML] Identification of a major carbohydrate capping group of the L-selectin ligand on high endothelial venules in human lymph nodes as 6-sulfo sialyl Lewis X
C Mitsuoka, M Sawada-Kasugai, K Ando-Furui… - Journal of Biological …, 1998 - ASBMB
We investigated the molecular species of sulfated sialyl Lewis X determinants, the putative L-
selectin ligand, expressed on high endothelial venules (HEV) in human lymph nodes.
Comparison of the reactivity pattern of HEV with the reactivity of the pure 6-sulfo, 6′-sulfo,
or 6, 6′-bissulfo sialyl Lewis X determinant with hitherto known anti-sialyl Lewis X
antibodies strongly suggested 6-sulfo sialyl Lewis X to be the best candidate for the major
sulfated sialyl Lewis X determinant on HEV, followed by 6, 6′-bissulfo sialyl Lewis X …
selectin ligand, expressed on high endothelial venules (HEV) in human lymph nodes.
Comparison of the reactivity pattern of HEV with the reactivity of the pure 6-sulfo, 6′-sulfo,
or 6, 6′-bissulfo sialyl Lewis X determinant with hitherto known anti-sialyl Lewis X
antibodies strongly suggested 6-sulfo sialyl Lewis X to be the best candidate for the major
sulfated sialyl Lewis X determinant on HEV, followed by 6, 6′-bissulfo sialyl Lewis X …
