[HTML][HTML] Two pathways to NF-κB
JL Pomerantz, D Baltimore - Molecular cell, 2002 - cell.com
JL Pomerantz, D Baltimore
Molecular cell, 2002•cell.comNF-κB is a transcription factor that is critical for innate and adaptive immunity. Recently, a
noncanonical pathway for NF-κB activation has emerged. Four recent papers provide
physiological roles for this pathway and expand our understanding of lymphoid
development and organogenesis with potential applications in the treatment of autoimmune
disease.
noncanonical pathway for NF-κB activation has emerged. Four recent papers provide
physiological roles for this pathway and expand our understanding of lymphoid
development and organogenesis with potential applications in the treatment of autoimmune
disease.
Abstract
NF-κB is a transcription factor that is critical for innate and adaptive immunity. Recently, a noncanonical pathway for NF-κB activation has emerged. Four recent papers provide physiological roles for this pathway and expand our understanding of lymphoid development and organogenesis with potential applications in the treatment of autoimmune disease.
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