Angiotensinogen genotype and blood pressure response in the Dietary Approaches to Stop Hypertension (DASH) study

LP Svetkey, TJ Moore, DG Simons-Morton… - Journal of …, 2001 - journals.lww.com
LP Svetkey, TJ Moore, DG Simons-Morton, LJ Appel, GA Bray, FM Sacks, JD Ard
Journal of hypertension, 2001journals.lww.com
Objective To determine the relationship between angiotensinogen (ANG) genotype and
blood pressure response to the dietary patterns of the Dietary Approaches to Stop
Hypertension (DASH) trial. The angiotensin converting enzyme (ACE) gene was also tested.
Design The DASH trial was a randomized outpatient feeding study comparing the effects on
blood pressure (BP) of three dietary patterns: a control diet, similar to typical American
intake; a 'fruits and vegetables' diet (F/V) that is rich in fruits and vegetables but otherwise …
Abstract
Objective
To determine the relationship between angiotensinogen (ANG) genotype and blood pressure response to the dietary patterns of the Dietary Approaches to Stop Hypertension (DASH) trial. The angiotensin converting enzyme (ACE) gene was also tested.
Design
The DASH trial was a randomized outpatient feeding study comparing the effects on blood pressure (BP) of three dietary patterns: a control diet, similar to typical American intake; a ‘fruits and vegetables’ diet (F/V) that is rich in fruits and vegetables but otherwise resembles the control diet; and the DASH diet that is reduced in fats and that emphasizes fruits, vegetables and low-fat dairy products. Participants’ genotype was also determined.
Setting
Lippincott Williams & Wilkins