TH1 and TH2 cells: a historical perspective
FY Liew - Nature Reviews Immunology, 2002 - nature.com
Nature Reviews Immunology, 2002•nature.com
Demonstration of the existence and functions of T helper (TH) 1 and TH2 cells has had an
enormous impact on basic and applied immunology. TH1 and TH2 cells have a crucial role
in balancing the immune response. In this article, I attempt to trace the historical events
contributing to the development of the TH1/TH2 concept, the current state of play, and briefly
discuss the future prospects for the field.
enormous impact on basic and applied immunology. TH1 and TH2 cells have a crucial role
in balancing the immune response. In this article, I attempt to trace the historical events
contributing to the development of the TH1/TH2 concept, the current state of play, and briefly
discuss the future prospects for the field.
Abstract
Demonstration of the existence and functions of T helper (TH)1 and TH2 cells has had an enormous impact on basic and applied immunology. TH1 and TH2 cells have a crucial role in balancing the immune response. In this article, I attempt to trace the historical events contributing to the development of the TH1/TH2 concept, the current state of play, and briefly discuss the future prospects for the field.
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