Empirical assessment of whether moderate payments are undue or unjust inducements for participation in clinical trials
SD Halpern, JHT Karlawish, D Casarett… - Archives of Internal …, 2004 - jamanetwork.com
Background Paying patients to participate in clinical trials is ethically controversial. However,
there has been no empirical documentation regarding whether payment represents an
undue or unjust inducement. Methods To evaluate these questions, we described
hypothetical placebo-controlled trials of a new antihypertensive drug to 126 patients with
mild-to-moderate hypertension recruited from hypertension and general medicine clinics at
a university hospital. Using a 3× 3, within-subjects design, we altered a risk to participation …
there has been no empirical documentation regarding whether payment represents an
undue or unjust inducement. Methods To evaluate these questions, we described
hypothetical placebo-controlled trials of a new antihypertensive drug to 126 patients with
mild-to-moderate hypertension recruited from hypertension and general medicine clinics at
a university hospital. Using a 3× 3, within-subjects design, we altered a risk to participation …
