Background Investigators have voiced concerns that distrust of research and the medical
community impedes successful recruitment of African Americans into clinical research.
Objectives To examine possible differences in distrust by race and to determine to what
extent other sociodemographic factors explain any racial differences in distrust. Methods We
analyzed data from 527 African American and 382 white respondents of a national
telephone survey on participation in clinical research. Our main outcome measure was a 7 …