Research participation by individuals who lack health insurance raises significant but
seldom-discussed ethical issues for clinical investigators. Of particular concern are the
possibility that their lack of options for getting care at the time of enrollment makes the
uninsured susceptible to undue inducement to join trials and the possibility that their inability
to access research products after trials leads to their exploitation. In tension with these
concerns, however, is the right of the uninsured to fair consideration for research …