Monocyte function in systemic lupus erythematosus
J Boswell, PH Schur - Clinical immunology and immunopathology, 1989 - Elsevier
Systemic lupus erythematousus (SLE) is characterized by multiple defects affecting B and T
lymphocyte cell function. In view of the influence that monocytes may have on these
functions, we have examined monocyte function in patients with SLE and normals.
Monocytes were examined as to number, their ability to modulate IgG synthesis,
phagocytose yeast particles, and acid phosphatase acivity. Patients had more monocytes
and mononuclear cells made more IgG, but these factors appear to be independent of each …
lymphocyte cell function. In view of the influence that monocytes may have on these
functions, we have examined monocyte function in patients with SLE and normals.
Monocytes were examined as to number, their ability to modulate IgG synthesis,
phagocytose yeast particles, and acid phosphatase acivity. Patients had more monocytes
and mononuclear cells made more IgG, but these factors appear to be independent of each …
