Some patients with allergic asthma exhibit late-phase responses to inhalation challenge
with specific antigen. However, the duration of these responses is difficult to determine
because of diurnal variations in airway function, a common phenomenon in patients with
asthma. We therefore examined the pattern and duration of pulmonary function in six
asymptomatic patients with a history of ragweed asthma and a documented late-phase
response after specific and nonspecific bronchial challenge and compared them to …