[HTML][HTML] Increase in intranuclear nuclear factor κB and decrease in inhibitor κB in mononuclear cells after a mixed meal: evidence for a proinflammatory effect

A Aljada, P Mohanty, H Ghanim, T Abdo… - The American journal of …, 2004 - Elsevier
Background In view of the stimulatory effect of glucose on reactive oxygen species (ROS)
generation, we investigated the possibility that a mixed meal stimulates ROS generation and
possibly induces concomitant proinflammatory changes. Objective The objective was to
determine whether the intake of a 900-kcal mixed meal induces an increase in ROS
generation by leukocytes and an inflammatory response at the cellular level. Design Nine
normal-weight subjects were given a 900-kcal mixed meal, and 8 normal-weight subjects …