Introduction: Tissue factor plays a key role in the extrinsic coagulation pathway and is
induced by inflammatory cytokines. Atrial myocarditis has been detected recently in some
patients with lone atrial fibrillation. Virchow's triad of low blood flow, hypercoagulability, and
endothelial dysfunction, enhances thrombus formation. The present study was designed to
elucidate the role of endothelial dysfunction in thrombogenesis associated with nonvalvular
atrial fibrillation. Material and methods: We investigated tissue factor expression in the …