Prostaglandins and the release of insulin: A review and a proposal
M Moran - Prostaglandins, Leukotrienes and Essential Fatty Acids, 1988 - Elsevier
The effect of prostaglandins or the inhibition of their synthesis on the release of insulin is
controversial. Dispute exists because there are apparently disparate experimental results.
When the following factors are considered, however, much of the disparity is eliminated: 1.
1) the experimental setting—in vitro or in vivo; 2. 2) the experimental model—animal or
human; 3. 3) the experimental additive—the type of nonsteroidal antiinflammatory drug or
specific prostaglandin; 4. 4) the relationship of insulin levels to insulin secretion …
controversial. Dispute exists because there are apparently disparate experimental results.
When the following factors are considered, however, much of the disparity is eliminated: 1.
1) the experimental setting—in vitro or in vivo; 2. 2) the experimental model—animal or
human; 3. 3) the experimental additive—the type of nonsteroidal antiinflammatory drug or
specific prostaglandin; 4. 4) the relationship of insulin levels to insulin secretion …