[HTML][HTML] PTEN enters the nuclear age

SJ Baker - Cell, 2007 - cell.com
SJ Baker
Cell, 2007cell.com
Regulation of the PTEN tumor suppressor protein is poorly understood. In this issue, Wang
et al.(2007) and Trotman et al.(2007) describe how ubiquitination regulates PTEN stability
and its nuclear localization. Additionally, Shen et al.(2007) report that a nuclear pool of
PTEN helps to maintain chromosomal stability.
Regulation of the PTEN tumor suppressor protein is poorly understood. In this issue, Wang et al. (2007) and Trotman et al. (2007) describe how ubiquitination regulates PTEN stability and its nuclear localization. Additionally, Shen et al. (2007) report that a nuclear pool of PTEN helps to maintain chromosomal stability.
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