Cushing's syndrome
TA Howlett, LH Rees, GM Besser - Clinics in endocrinology and …, 1985 - Elsevier
Cushing's syndrome remains one of the most challenging problems in clinical
endocrinology. Cushing's disease is caused in the majority of cases by basophil pituitary
microadenomas which may be successfully treated by trans-sphenoidal hypophysectomy.
Treatment with metyrapone or o, p′-DDD can always induce a clinical remission but not a
cure, and neurotransmitter therapy may be effective in a minority of cases. Pituitary
irradiation cures about half of cases in the long-term and may be used for surgical failures …
endocrinology. Cushing's disease is caused in the majority of cases by basophil pituitary
microadenomas which may be successfully treated by trans-sphenoidal hypophysectomy.
Treatment with metyrapone or o, p′-DDD can always induce a clinical remission but not a
cure, and neurotransmitter therapy may be effective in a minority of cases. Pituitary
irradiation cures about half of cases in the long-term and may be used for surgical failures …