Stroke is devastating as currently no therapies are available that can prevent stroke-induced
neurological dysfunction in humans. With the recent observations that acute insults to adult
brain stimulate new neuronal formation in various species of animals, optimism is building
for a possible regeneration of stroke-damaged brain. This article reviewed the advances in
the understanding of the molecular mechanisms of the various steps of neurogenesis with
an emphasis on the endogenous mediators and exogenous promoters of neural progenitor …