High-density lipoprotein as a therapeutic target: a systematic review

IM Singh, MH Shishehbor, BJ Ansell - Jama, 2007 - jamanetwork.com
ContextHigh-density lipoprotein cholesterol (HDL-C) is a cardiovascular risk factor that is
gaining substantial interest as a therapeutic target. ObjectivesTo review the current and
emerging strategies that modify high-density lipoproteins (HDLs). Data SourcesSystematic
search of English-language literature (1965-May 2007) in MEDLINE and the Cochrane
database, using the key words HDL-C and apolipoprotein AI and the subheadings reverse
cholesterol transport, CVD [cardiovascular disease] prevention and control, drug therapy …