Effect of serologic status and cesarean delivery on transmission rates of herpes simplex virus from mother to infant

ZA Brown, A Wald, RA Morrow, S Selke, J Zeh, L Corey - Jama, 2003 - jamanetwork.com
Context Neonatal herpes most commonly results from fetal exposure to infected maternal
genital secretions at the time of delivery. The risk of transmission from mother to infant as it
relates to maternal herpes simplex virus (HSV) serologic status and exposure to HSV in the
maternal genital tract at the time of labor has not been quantified. Furthermore, no data exist
on whether cesarean delivery, the standard of care for women with genital herpes lesions at
the time of delivery, reduces HSV transmission. Objective To determine the effects of viral …