A pooled analysis of the effect of condoms in preventing HSV-2 acquisition

ET Martin, E Krantz, SL Gottlieb… - Archives of internal …, 2009 - jamanetwork.com
Background The degree of effectiveness of condom use in preventing the transmission of
herpes simplex virus 2 (HSV-2) is uncertain. To address this issue, we performed a large
pooled analysis. Methods We identified prospective studies with individual-level condom
use data and laboratory-defined HSV-2 acquisition. Six studies were identified through a
review of publications through 2007: 3 candidate HSV-2 vaccine studies, an HSV-2 drug
study, an observational sexually transmitted infection (STI) incidence study, and a …