Dendritic cells (DCs) are specialized antigen-presenting cells that orchestrate innate and
adaptive immune responses. The intestinal mucosa contains numerous DCs that are highly
specialized in function. Mucosal DCs display a unique response to toll-like receptor ligands,
are capable of driving immunoglobulin isotype switching to IgA, can imprint gut-homing
receptors on T and B cells, and drive either T regulatory or Th17 cells depending on the
analyzed subtype. These functions are partly cell autonomous and partly conferred by the …