p53, guardian of the genome.

DP Lane - Nature, 1992 - search.ebscohost.com
Nature, 1992search.ebscohost.com
Relates that research on the p53 protein is at fever pitch. Evidence that inactivation of its
tumor-suppressor activity is an almost universal step in the development of human cancers;
Work of Momand, et al, who have identified a rat protein that co-immunoprecipitates with p53
(ref. 3) as the rat homologue of the mouse MDM2 protein; More.
Abstract
Relates that research on the p53 protein is at fever pitch. Evidence that inactivation of its tumor-suppressor activity is an almost universal step in the development of human cancers; Work of Momand, et al, who have identified a rat protein that co-immunoprecipitates with p53 (ref. 3) as the rat homologue of the mouse MDM2 protein; More.
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