[PDF][PDF] Oxidized LDLs trigger endoplasmic reticulum stress and autophagy: prevention by HDLs
C Muller, R Salvayre, A Nègre-Salvayre, C Vindis - Autophagy, 2011 - Taylor & Francis
C Muller, R Salvayre, A Nègre-Salvayre, C Vindis
Autophagy, 2011•Taylor & FrancisOxidized LDLs (oxLDLs) induce various cellular dysfunctions potentially implicated in the
pathogenesis of atherosclerosis. For instance, toxic concentrations of oxLDLs trigger ER
stress, autophagy and apoptosis. High-density lipoproteins (HDLs) counteract several
adverse biological effects triggered by oxLDLs. Our recent study reveals that HDLs inhibit
the activation of ER stress and of autophagy induced by oxLDLs.
pathogenesis of atherosclerosis. For instance, toxic concentrations of oxLDLs trigger ER
stress, autophagy and apoptosis. High-density lipoproteins (HDLs) counteract several
adverse biological effects triggered by oxLDLs. Our recent study reveals that HDLs inhibit
the activation of ER stress and of autophagy induced by oxLDLs.
Oxidized LDLs (oxLDLs) induce various cellular dysfunctions potentially implicated in the pathogenesis of
atherosclerosis. For instance, toxic concentrations of oxLDLs trigger ER stress, autophagy and apoptosis. High-density lipoproteins (HDLs) counteract several adverse biological effects triggered by oxLDLs. Our recent study reveals that HDLs inhibit the activation of ER stress and of autophagy induced by oxLDLs.
Taylor & Francis Online