The discovery of anthranilic acid-Based MMP inhibitors. Part 2: SAR of the 5-position and P11 groups

JI Levin, J Chen, M Du, M Hogan, S Kincaid… - Bioorganic & medicinal …, 2001 - Elsevier
JI Levin, J Chen, M Du, M Hogan, S Kincaid, FC Nelson, AM Venkatesan, T Wehr, A Zask
Bioorganic & medicinal chemistry letters, 2001Elsevier
The discovery of anthranilic acid-Based MMP inhibitors. Part 2: SAR of the 5-position and P11
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Volume 11, Issue 16, 20 August 2001, Pages 2189-2192 Bioorganic & Medicinal Chemistry Letters
The discovery of anthranilic acid-Based MMP inhibitors. Part 2: SAR of the 5-position and P1 1
groups Author links open overlay panel JI Levin a , J. Chen a , M. Du a , M. Hogan a , S. Kincaid …
A novel series of anthranilic acid-based inhibitors of MMP-1, MMP-9, MMP-13, and TACE was prepared and evaluated. Selective inhibitors of MMP-9, MMP-13, and TACE were identified, including the potent, orally active MMP-13 inhibitor 4p.
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