The painful crisis of homozygous sickle cell disease: a study of risk factors
KF Baum, DT Dunn, GH Maude… - Archives of internal …, 1987 - jamanetwork.com
• Some epidemiologic features of the painful crisis In homozygous sickle cell disease were
examined in a retrospective study of 995 painful crises. Previously reported associations
with cold weather and pregnancy were confirmed. There was a striking increase in painful
crises in male patients between the ages of 15 and 25 years, whereas female patients
showed little age-related change. The frequency of painful crises correlated positively with
hemoglobin levels and reticulocyte counts in both sexes and negatively with mean …
examined in a retrospective study of 995 painful crises. Previously reported associations
with cold weather and pregnancy were confirmed. There was a striking increase in painful
crises in male patients between the ages of 15 and 25 years, whereas female patients
showed little age-related change. The frequency of painful crises correlated positively with
hemoglobin levels and reticulocyte counts in both sexes and negatively with mean …