N-terminal pro-brain natriuretic peptide levels and risk of death in sickle cell disease
RF Machado, A Anthi, MH Steinberg, D Bonds… - Jama, 2006 - jamanetwork.com
ContextThirty percent of patients with sickle cell disease (SCD) develop pulmonary
hypertension, a major risk factor for death in this population. A validated blood biomarker of
pulmonary hypertension in SCD could provide important prognostic and diagnostic
information and allow the exploration of the prevalence of pulmonary hypertension in
participants in the 1996 Multicenter Study of Hydroxyurea in Sickle Cell Anemia (MSH)
Patients' Follow-up Study. Levels of N-terminal pro-brain natriuretic peptide (NT-proBNP) …
hypertension, a major risk factor for death in this population. A validated blood biomarker of
pulmonary hypertension in SCD could provide important prognostic and diagnostic
information and allow the exploration of the prevalence of pulmonary hypertension in
participants in the 1996 Multicenter Study of Hydroxyurea in Sickle Cell Anemia (MSH)
Patients' Follow-up Study. Levels of N-terminal pro-brain natriuretic peptide (NT-proBNP) …