Pulmonary hypertension in sickle cell disease
KI Ataga, N Sood, G De Gent, E Kelly… - The American journal of …, 2004 - Elsevier
BACKGROUND: Recurrent vaso-occlusive episodes lead to progressive end-organ damage
in patients with sickle cell disease. We sought to determine the prevalence of pulmonary
hypertension in adult patients with sickle cell disease and to identify factors associated with
this life-threatening complication. METHODS: Sixty patients (≥ 18 years of age; mean [±SD]
age, 37±13 years) followed at a University Medical Center were evaluated. They were
selected by a systematic sampling of patients presenting to the clinic for routine follow-up …
in patients with sickle cell disease. We sought to determine the prevalence of pulmonary
hypertension in adult patients with sickle cell disease and to identify factors associated with
this life-threatening complication. METHODS: Sixty patients (≥ 18 years of age; mean [±SD]
age, 37±13 years) followed at a University Medical Center were evaluated. They were
selected by a systematic sampling of patients presenting to the clinic for routine follow-up …