Cellular adhesion and the endothelium: P-selectin
A Kutlar, SH Embury - Hematology/Oncology Clinics, 2014 - hemonc.theclinics.com
The importance of P-selectin to the pathophysiology of sickle cell disease (SCD) is
understood through its effect on blood flow. P-selectin is central to the abnormal blood flow
in SCD, and abnormal blood flow is paramount to the morbidity and mortality of the disorder.
Although the expression of P-selectin makes important contributions to normal platelet
activity, hemostasis, coagulation, and inflammation, 1–4 the focus of
understood through its effect on blood flow. P-selectin is central to the abnormal blood flow
in SCD, and abnormal blood flow is paramount to the morbidity and mortality of the disorder.
Although the expression of P-selectin makes important contributions to normal platelet
activity, hemostasis, coagulation, and inflammation, 1–4 the focus of