[HTML][HTML] Potential genetic risk factors for chronic TMD: genetic associations from the OPPERA case control study

SB Smith, DW Maixner, JD Greenspan, R Dubner… - The Journal of …, 2011 - Elsevier
Genetic factors play a role in the etiology of persistent pain conditions, putatively by
modulating underlying processes such as nociceptive sensitivity, psychological well-being,
inflammation, and autonomic response. However, to date, only a few genes have been
associated with temporomandibular disorders (TMD). This study evaluated 358 genes
involved in pain processes, comparing allelic frequencies between 166 cases with chronic
TMD and 1,442 controls enrolled in the OPPERA (Orofacial Pain: Prospective Evaluation …