Method for assessing the similarity between subsets of the T cell receptor repertoire

V Venturi, K Kedzierska, MM Tanaka, SJ Turner… - Journal of …, 2008 - Elsevier
The CD8+ T cell response is important in the control of many viral and other infections.
There have been many studies aimed at better understanding the influence of T cell receptor
diversity on immune responses and the evolution of the T cell receptor repertoire over time
and through the various stages of immune responses to infection. In recent years, there has
been an increase in both the number of studies using T cell receptor data and the volume of
T cell receptor data generated per study. Appropriate analytical tools are required to analyse …