[HTML][HTML] Transcription elongation regulator 1 is a co-integrator of the cell fate determination factor Dachshund homolog 1
J Zhou, Y Liu, W Zhang, VM Popov, M Wang… - Journal of biological …, 2010 - ASBMB
DACH1 (Dachshund homolog 1) is a key component of the retinal determination gene
network and regulates gene expression either indirectly as a co-integrator or through direct
DNA binding. The current studies were conducted to understand, at a higher level of
resolution, the mechanisms governing DACH1-mediated transcriptional repression via DNA
sequence-specific binding. DACH1 repressed gene transcription driven by the DACH1-
responsive element (DRE). Recent genome-wide ChIP-Seq analysis demonstrated DACH1 …
network and regulates gene expression either indirectly as a co-integrator or through direct
DNA binding. The current studies were conducted to understand, at a higher level of
resolution, the mechanisms governing DACH1-mediated transcriptional repression via DNA
sequence-specific binding. DACH1 repressed gene transcription driven by the DACH1-
responsive element (DRE). Recent genome-wide ChIP-Seq analysis demonstrated DACH1 …