Association of elevated serum PO4, Ca× PO4 product, and parathyroid hormone with cardiac mortality risk in chronic hemodialysis patients
Hyperphosphatemia is highly prevalent among patients with end-stage renal disease
(ESRD) and is associated with increased mortality risk in hemodialysis (HD) patients. The
mechanism through which this mortality risk is mediated is unclear. Data from two national
random samples of HD patients (n= 12,833) was used to test the hypothesis that elevated
serum PO 4 contributes mainly to cardiac causes of death. During a 2-yr follow-up, the cause-
specific relative risk (RR) of death for patients was analyzed separately for several …
(ESRD) and is associated with increased mortality risk in hemodialysis (HD) patients. The
mechanism through which this mortality risk is mediated is unclear. Data from two national
random samples of HD patients (n= 12,833) was used to test the hypothesis that elevated
serum PO 4 contributes mainly to cardiac causes of death. During a 2-yr follow-up, the cause-
specific relative risk (RR) of death for patients was analyzed separately for several …