A modified fluorescent microsphere-based approach for determining resting and hyperemic blood flows in individual murine skeletal muscles

TR Cardinal, JB Hoying - Vascular pharmacology, 2007 - Elsevier
The goal of this study was to develop a modified fluorescent microsphere-based approach
for measuring resting and hyperemic blood flows in individual mouse skeletal muscles.
Absolute resting blood flow in the left gracilis posterior was 1.04±0.12 ml· min− 1· g− 1, while
functional hyperemia following muscle activity was 5.94±1.33 ml· min− 1· g− 1. Measuring
absolute blood flow requires sampling arterial blood that serves as a flow-rate and
concentration reference to the fluorescent microsphere (FMS) content in the tissue-of …