Initial SRS for patients with 5 to 15 brain metastases: results of a multi-institutional experience
Purpose Several studies evaluating stereotactic radiosurgery (SRS) for patients with> 4
brain metastases (BM) demonstrated similar outcomes after treatment of 1, 2 to 4, and 5 to
15 BM; others found clinically significant survival decrements in the latter group. In this
review of 8 academic centers, we compared outcomes of patients undergoing initial SRS for
1, 2 to 4, and 5 to 15 BM. Methods and Materials A total of 2089 patients treated with initial
SRS for BM were included. Overall survival (OS) was estimated using the Kaplan-Meier …
brain metastases (BM) demonstrated similar outcomes after treatment of 1, 2 to 4, and 5 to
15 BM; others found clinically significant survival decrements in the latter group. In this
review of 8 academic centers, we compared outcomes of patients undergoing initial SRS for
1, 2 to 4, and 5 to 15 BM. Methods and Materials A total of 2089 patients treated with initial
SRS for BM were included. Overall survival (OS) was estimated using the Kaplan-Meier …