[HTML][HTML] Type V collagen controls the initiation of collagen fibril assembly
RJ Wenstrup, JB Florer, EW Brunskill, SM Bell… - Journal of Biological …, 2004 - ASBMB
Vertebrate collagen fibrils are heterotypically composed of a quantitatively major and minor
fibril collagen. In non-cartilaginous tissues, type I collagen accounts for the majority of the
collagen mass, and collagen type V, the functions of which are poorly understood, is a minor
component. Type V collagen has been implicated in the regulation of fibril diameter, and we
reported recently preliminary evidence that type V collagen is required for collagen fibril
nucleation (Wenstrup, RJ, Florer, JB, Cole, WG, Willing, MC, and Birk, DE (2004) J. Cell …
fibril collagen. In non-cartilaginous tissues, type I collagen accounts for the majority of the
collagen mass, and collagen type V, the functions of which are poorly understood, is a minor
component. Type V collagen has been implicated in the regulation of fibril diameter, and we
reported recently preliminary evidence that type V collagen is required for collagen fibril
nucleation (Wenstrup, RJ, Florer, JB, Cole, WG, Willing, MC, and Birk, DE (2004) J. Cell …