Transcriptional regulation by the phosphorylation-dependent factor CREB

B Mayr, M Montminy - Nature reviews Molecular cell biology, 2001 - nature.com
B Mayr, M Montminy
Nature reviews Molecular cell biology, 2001nature.com
The transcription factor CREB? for'cyclic AMP response element-binding protein'? functions
in glucose homeostasis, growth-factor-dependent cell survival, and has been implicated in
learning and memory. CREB is phosphorylated in response to various signals, but how is
specificity achieved in these signalling pathways?
Abstract
The transcription factor CREB ? for 'cyclic AMP response element-binding protein' ? functions in glucose homeostasis, growth-factor-dependent cell survival, and has been implicated in learning and memory. CREB is phosphorylated in response to various signals, but how is specificity achieved in these signalling pathways?
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