[HTML][HTML] Benefits and risks of dual versus single antiplatelet therapy for secondary stroke prevention: a systematic review for the 2021 guideline for the prevention of …

DL Brown, DA Levine, K Albright, MK Kapral, LY Leung… - Stroke, 2021 - journals.lww.com
Background: Dual antiplatelet therapy (DAPT) after ischemic stroke or transient ischemic
attack may reduce recurrent stroke but also increase severe bleeding compared with single
antiplatelet therapy (SAPT). The American Heart Association/American Stroke Association
convened an evidence review committee to perform a systematic review and meta-analysis
of the benefits and risks of DAPT compared with SAPT for secondary ischemic stroke
prevention. Methods: The Medline, Embase, and Cochrane databases were searched on …