[HTML][HTML] Protease‐activated receptor‐mediated platelet aggregation in acute coronary syndrome patients on potent P2Y12 inhibitors
PP Wadowski, J Pultar, C Weikert… - Research and practice …, 2019 - Elsevier
Background Despite the increasing use of potent P2Y 12 inhibitors, further atherothrombotic
events still impair the prognosis of many acute coronary syndrome (ACS) patients. This may
in part be attributable to intact platelet aggregation via the human thrombin receptors
protease‐activated receptor (PAR)‐1 and PAR‐4. Objective We studied PAR mediated
platelet aggregation in ACS patients following percutaneous coronary intervention (PCI) with
stent implantation in a cross‐sectional study. Methods Platelet aggregation to ADP as well …
events still impair the prognosis of many acute coronary syndrome (ACS) patients. This may
in part be attributable to intact platelet aggregation via the human thrombin receptors
protease‐activated receptor (PAR)‐1 and PAR‐4. Objective We studied PAR mediated
platelet aggregation in ACS patients following percutaneous coronary intervention (PCI) with
stent implantation in a cross‐sectional study. Methods Platelet aggregation to ADP as well …