Recognition of the DNA minor groove by pyrrole-imidazole polyamides

PB Dervan, BS Edelson - Current opinion in structural biology, 2003 - Elsevier
PB Dervan, BS Edelson
Current opinion in structural biology, 2003Elsevier
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Biology Volume 13, Issue 3, June 2003, Pages 284-299 Current Opinion in Structural
Biology Recognition of the DNA minor groove by pyrrole-imidazole polyamides Author links
open overlay panel Peter B Dervan , Benjamin S Edelson Show more Share Cite https://doi.org/10.1016/S0959-440X(03)00081-2 …
Many diseases, such as cancer, are related to aberrant gene expression. Regulating transcription by chemical methods could be important in human medicine. Minor groove-binding polyamides offer one chemical approach to DNA recognition.
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